Guyana
Monterey BayMonterey Bay
Chicago FireChicago Fire
Lexington3–2Monterey Bay
Atlanta United2–2Chicago FireChicago Fire1–2San Diego FC
FC Cincinnati2–1Chicago FireChicago Fire3–2Charlotte FC
Chicago Fire0–1Philadelphia Union
Chicago Fire0–2Nashville SC
Orlando City1–3Chicago Fire
New York City FC3–1Chicago FireCharlotte FC1–4Chicago FireChicago Fire2–1Atlanta UnitedChicago Fire0–0Orlando CityNashville SC7–2Chicago FireChicago Fire2–3FC CincinnatiChicago Fire0–0Inter Miami
New York Red Bulls2–1Chicago FireChicago Fire1–1CF Montreal
Toronto FC1–2Chicago Fire
FC Dallas1–3Chicago FireChicago Fire2–2DC United
Columbus Crew4–2Chicago FireChicago Fire0–1Charlotte FC
St. Louis City SC3–1Chicago FireChicago Fire0–1New England Revolution
